Revolutionizing Oral Fluid Toxicology with the SPEctra™ mSPE Kit

CURA Diagnostics' Xpeedy® SPEctra™ magnetic beads solid phase extraction (mSPE) kit represents a breakthrough in oral fluid (OF) drug of abuse (DOA) testing. This next-generation sample prep solution enables laboratories to fully automate OF extraction workflows without compromising sensitivity, precision or cost.

Traditional SPE methods are slow, labor-intensive, and hard to scale, limiting broader adoption of oral fluid testing. SPEctra™ solves this with a streamlined, automation-ready protocol that drastically reduces hands-on time while delivering robust, reproducible LC-MS/MS results across a wide range of target drugs.

In this study, SPEctra™ demonstrates strong recovery, low matrix effects, and industry-leading precision, even for low-abundance analytes. Compared to manual SPE, the kit cuts prep time more than in half for 96-sample batches, enabling labs to increase throughput while maintaining analytical quality.

Why Choose SPEctra™ ?

● Automation-Ready: Seamless integration with magnetic beads processors like the Thermo KingFisher Flex™ and CURA’s Xpeedy ® Autopure 96.

● High Performance: Recovery and matrix effects meet or exceed validation standards across 56 analytes.

● Superior Precision: Outperforms manual SPE with consistently better precision spanning linear ranges

● Time-Saving: More than 50% faster than manual methods for a full 96-well plate.

● Clinically Relevant LOQs: Achieves some of the lowest cutoffs in the industry for oral fluid toxicology.

● Versatility: Adaptable to other prominent sample types.

SPEctra™ makes oral fluid toxicology practical, scalable, and lab friendly. Download the full application note below to explore validation results, workflow, and analytical data.

Product Flyer: SPEctra Flyer REV 08142025.pdf

Application Note: CDAN001 REV072125.pdf