Revolutionizing Oral Fluid Toxicology with the Xpeedy™ mSPE System

The next-generation Xpeedy™ mSPE magnetic beads solid phase extraction (mSPE) kit represents a breakthrough in oral fluid drug of abuse testing. Fully automate laboratory oral fluid extraction workflows without compromising sensitivity, precision, or cost.

Traditional SPE methods are slow, labor-intensive, and difficult to scale—limiting broader adoption of oral fluid testing. Xpeedy™ mSPE tackles these challenges with a streamlined, automation-ready protocol, drastically reducing hands-on time while delivering robust, reproducible LC-MS/MS results across a wide range of target drugs.

In this study, Xpeedy™ mSPE demonstrates strong recovery, low matrix effects, and industry-leading precision, even for low-abundance analytes. Compared to manual SPE, our kit cuts prep time by over half for 96-sample batches. Your lab increases throughput and maintains analytical quality. 

Why Choose Xpeedy™ mSPE?

● Automation-Ready: Seamless integration with magnetic beads processors like the Thermo KingFisher Flex™ and CURA’s Xpeedy ® Autopure 96.

● High Performance: Recovery and matrix effects meet or exceed validation standards across 56 analytes.

● Superior Precision: Outperforms manual SPE with consistently better precision spanning linear ranges

● Efficient: More than 50% faster than manual methods for a full 96-well plate.

● Clinically Relevant LOQs: Achieves some of the lowest cutoffs in the industry for oral fluid toxicology.

● Versatility: Adaptable to other prominent sample types.

 Xpeedy™ mSPE reimagines oral fluid toxicology as practical, scalable, and lab friendly. Explore validation results, workflow, and analytical data below

Product Flyer: SPEctra Flyer REV 08142025.pdf

Application Note: CDAN001 REV072125.pdf